Doctor measure the waist of a make patient

Vine Vera Researches: Resveratrol a Cure For Metabolic Syndrome? VineVera Reviews

Resveratrol, a natural compound that is found in red wine and in the skin of red grapes, has emerged as one of the most popular skin care ingredients in the world. Vine Vera uses Resveratrol as its signature ingredient, primarily because of the wonders that it has to offer to one’s skin. There are numerous studies that have already shown the wonders that Resveratrol has to offer as a skin care ingredient. However, many more studies that can take Resveratrol research and its uses to an entirely new level are currently in various stages of completion.

Vine Vera reviews a study that was published in the Journal of Clinical Endocrinology & Metabolism. The authors of this study are a group of Danish researchers who tried to determine whether or not Resveratrol could help cure metabolic syndromes, an issue that can cause bone loss. Metabolic syndromes have been linked to low-level inflammation and it is basically a cluster of risk factors that can increase the chances of things like diabetes, heart diseases and strokes. Some of the main risk factors that the body goes through when suffering from the metabolic syndrome include high levels of triglycerides, increased blood pressure, abdominal obesity and reduced density of good cholesterol levels.

According to Marie Juul Ørnstrup, one of the authors of the study who works for the Aarhus University Hospital, Denmark; this study is the first Resveratrol study that tries to determine the potential of Resveratrol as an anti-osteoporosis drug that can help humans.

This study was performed as a double-blinded, placebo controlled trial that tried to assess the signs of bone formation and resorption and bone mineral density in sixty six men who suffered from metabolic syndrome. This trial went on for a period of 16 weeks, where the men were either made to take a placebo, a 500mg dose of Resveratrol or a 75mg dose of Resveratrol two times a day.

According to the results of the trial, men who took the 500mg dose of Resveratrol saw an increase of almost 2.6% in terms of the volumetric bone mineral density of the lumbar spine. Moreover, the group of men who were offered a higher percentage of Resveratrol also managed to see a 16% increase in the BAP levels (Bone formation marker Alkaline Phosphatase levels) when compared to the rest of the group.

Marie states that the findings of this study state that the Resveratrol can actually stimulate the bone-forming cells within the human body. She also mentions that within just four months of being offered with a high dose of Resveratrol, the study observed a significant increase in the BAP levels as well as improvements in the bone mineral density.

Marie believes that this study has actually offered the scientific world with highly encouraging results. Although additional research is still needed before it can be ascertained whether Resveratrol can actually offer these wonders and whether Resveratrol can be used for long-term treatments, but experts from the skin care and scientific world are already excited to find out yet another wonder that Resveratrol has to offer.

Woman drinking red wine

Resveralife Examines the Relationship Between Red Wine and Acne

Red wine contains an antioxidant that is believed to help in the treatment of acne. Vine Vera reviews a new study which states that red wine is a major enemy of acne because of the presence of an antioxidant known as Resveratrol. Resveratrol has certain acne-fighting properties and is usually found in the skin of red grapes. Thus, this ingredient automatically finds its way into red wine and it hinders the growth of the bacteria which causes acne.

Resveratrol is the same substance that has become one of the “darling ingredients” of the skin care world because of its anti-aging benefits. Many doctors have also recommended drinking red wine because of the health-heart properties that Resveratrol has to offer. Furthermore, Resveratrol prevents the growth of free radicals that can cause tissue or cell damage in the body.

This study was conducted by researchers from the University of California Los Angeles (UCLA). According to a report in The Independent Journal, the UCLA experts tested the acne fighting properties of red wine by using the blood samples of healthy volunteers who did not have such skin conditions. It used this blood to test the ability of Resveratrol in inhibiting the growth of acne causing bacteria and found that Resveratrol was actually effective. However, it is important to note that the best acne fighters were not just centered around Resveratrol. The report suggests that the best results were derived when Resveratrol was used in combination with Benzoyl peroxide. Benzoyl peroxide basically works by creating free radicals which kill the acne-causing bacteria.

The team grew acne-causing bacteria and then used different combinations of Benzoyl peroxide and Resveratrol to see which combinations worked the best. These cultures were monitored for 10 days to record the level of bacteria growth or bacteria killing. Benzoyl peroxide displayed a great ability to kill acne-causing bacteria in all concentrations, but its effects were short lived. On the other hand, Resveratrol did not display a decent killing capability, but it managed to inhibit bacteria growth for a longer period of time.

Initially, experts were against combining Resveratrol and Benzoyl peroxide because Resveratrol is a known anti-oxidant and Benzoyl peroxide is an oxidant. Thus, it was thought that they would cancel out each other’s effects. However, reports suggest that this was not the case. They proved to be a formidable combination because they portrayed anti-bacterial activity in the initial stages as well as a sustained bacterial growth inhibition.

According to Dr. Emma Taylor, one of the researchers associated with the UCLA study, the study shows that combining antioxidants with oxidants can enhance the effectiveness of each ingredient in fighting bacteria over a long period of time. This study should also lead to the development of acne treatments that are less invasive.

Dr. Jenny Kim, the professor of clinical medicine at the Geffen School, states that adding these two ingredients was quite similar to combining the best ingredients from both words and using a two-pronged attack to deal with acne-causing bacteria.

Taylor mentioned that she hopes that their findings lead to the development of a new category of acne therapies are based on antioxidants. The next steps of this research involve laboratory testings to better understand both compounds and their acne-fighting capabilities.

Woman holding a breast cancer ribbon

Study Identifies Resveratrol's Ability to Inhibit Cancer

A chemical found in the skin of red grapes and in red wine, is considered to be extremely effective in fighting cancer, even after the metabolism present in the human body converts this chemical into other compounds. Vine Vera reviews a study that was published in the Science Translational Medicine Journal confirms.

This study was conducted by a group of researchers working for the Department of Cancer Studies and Molecular Medicine at the University of Leicester. This study reveals that Resveratrol, a popular antioxidant found in red wine, doesn’t become ineffective after it has been metabolized by the body.

This proves to be an extremely important finding that shows the effectiveness of Resveratrol in the human body, because recent studies had shown that Resveratrol gets metabolized very quickly, thereby raising questions on its effectiveness. This new research also shows that Resveratrol can still be taken in by the cells, even after it has been transformed into Resveratrol sulfates by the body’s metabolism.

The study also shows that enzymes present within the cells manage to break down the Resveratrol sulfates back into Resveratrol. In fact, this study actually shows that Resveratrol might be even more effective once it is transformed from Resveratrol sulfates, because of the higher concentrations.

The team had administered Resveratrol sulfates into mice to further their research. They subsequently managed to detect the presence of free Resveratrol in a variety of tissues and the plasma of mice. This is the first direct sign of the fact that Resveratrol sulfates can be transformed back into Resveratrol by the body, thereby leading researchers to believe that the compound might be even more beneficial than initially thought.

The study also confirmed that the Resveratrol generated from the Resveratrol sulfates can actually slow down the growth of cancer cells by forcing them to digest their own constituents and preventing them from dividing further.

According to Professor Karen Brown, there is some serious evidence from the lab testings that Resveratrol can not just prevent a variety of cancers, but can also protect the body from heart diseases in order to extend the lifespan of the body. It is common knowledge that Resveratrol rapidly converts into sulfates in animals.

This means that the plasma concentrations of Resveratrol become low after administration. Professor Brown states that it was always difficult for experts to understand how Resveratrol managed to offer its benefits when the concentrations were so low. She also mentions that this was one of the main reasons why many experts were doubtful if Resveratrol had any effects whatsoever on humans.

However, the latest study has actually shown that the compound can be regenerated into a more potent form and that this compound can then offer biological activity to the body in order to make itself useful in treating all sorts of diseases. However, most of these discoveries have been made in laboratory settings. Whether or not the compound actually manages to offer such benefits to humans remains to be seen.

Dr. Sarah Williams, the health information officer of Cancer Research UK, mentioned that this study supports the continued research into Resveratrol. She also mentioned that it was important to note that none of the effects were because of drinking red wine and that consuming any sort of alcohol, red wine included, increases the chances of developing cancer.

Sirtuin structure

Resveralife Examines the Link Between Resveratrol and Longetivity

Vine Vera reviews a recent study that shows how important this Sirutins are for the aging process.

 

This study focused on the SIRT3 gene, a gene that is found in the mitochondria of the cell. It seems that the age gap usually occurs because the system doesn’t function as well as it used to when the body was younger, it suffers from oxidative stress and over the years the stress levels build up as well. Under such conditions, the normal anti-oxidative system cannot take care of the body. This is when it gives into aging.

 

Reports suggest that researchers have finally managed to actually turn back the molecular clock in the blood stem cells of mice by infusing them with a unique longevity gene. Yes, you got that right. The experiment actually managed to rejuvenate aged stem cells, thereby providing new hope for the development of cures for age related diseases in human beings. This study was conducted by the University of California, Berkeley. Researchers associated with the tests believe and this study provides new hope for advancements in the understanding of molecular mechanisms. The findings of the study were also published in the Cell Reports Journal.

 

According to biologists, the SIRT3 gene, a gene that is found in the Sirtuin proteins, played a huge role in allowing aged stem cells to be able to cope up with stress. Researchers infused the blood stem cells of old mice with SIRT3. This led to the formation of new blood cells, thereby representing a reversal in the age decline of the stem cell function of the aged cell.

 

Danica Chen, the head investigator of the study mentions that it is already known that Sirtuins can regulate aging. However, this study can show that Sirtuins can actually reverse age-related degeneration. This is by far one of the most exciting discoveries made by the medical industry since the discovery of Resveratrol.

 

Over the past 10 – 20 years, scientists have managed to make countless breakthroughs when it comes to aging. We might not have the Fountain of Youth as yet, but we’re definitely close. Instead of a being a random and uncontrolled process, aging can actually be controlled. It is believed that as science progresses further, the secrets to the Fountain of Youth shall finally be unlocked in front of mankind.

 

A couple of studies conducted in the recent past had also shown how Resveratrol, the red wine compound, is beneficial for the skin and the body. These studies had shown that Resveratrol is an excellent antioxidant which protects the body from free radical damage and damage from the UVA and UVB rays of the sun. It is also known to be the only polyphenol that can activate the SIRT1 gene. The SIRT1 gene helps in promoting the creation of new cells and also goes a  long way in ensuring that the old ones last for longer.

 

Thus, when you combine the studies of this SIRT1 gene to the results obtained in the University of California study, the results actually look quite promising for all those looking for solutions to aging. It remains to be seen whether the SIRT3 gene can actually help in prolonging life, but Danica pointed out that this wasn’t the main goal of the research. She stated that the main goal was to use the knowledge to treat age-related diseases. Well, if not aging, we’re also happy with the next best thing – cures to age-related diseases.

Glass of red wine and eye glasses

Resveralife Examines the Connection Between Red Wine and Your Vision

It is a common fact that drinking way too much of alcohol can end up damaging your vision. However, studies have also managed to prove that drinking red wine can actually have a positive effect on your vision as it prevents your eyesight from deteriorating. But, before you open another bottle of red wine to celebrate, let’s read on a bit.

According to a group of researchers affiliated with the Washington University School of Medicine, St. Louis; Resveratrol, a substance that is found in extremely high levels in the skin of red grapes, can prevent the growth of harmful blood vessels. This helps the compound to protect the vessels in your eyes from aging damage. Apart from anti-aging, Resveratrol has been commonly linked to the deterrence of an eye condition known as AMD (Age-related Macular Degeneration) and the prevention of cancer.

Vine Vera reviews reports released by the CDC (Center for Disease Control and Prevention) which state that almost 11 million people suffer from AMD in the US. These reports also suggest that the number of people suffering from AMD should increase to almost 18 million in the year 2050. This disease is basically a condition where a part of the retina (towards the center) as well as the part of the eye which is necessary for sharp vision gets damaged. AMD is also known to be the main cause of vision loss among adults over the age of 50.

According to Sandy T. Feldman, a popular ophthalmologist in San Diego, people have begun to look for ways to prevent and treat common eye disorders including AMD. This new study might come across as a pleasant surprise for all such people because red wine is a favorite for countless people across the globe. To understand that it might have certain health benefits, is certainly pleasing.

Resveratrol is commonly found in the skin of red grapes, but its benefits can also be found in raspberries, cranberries, blueberries and peanuts. Of course, moderation is the key when it comes to any form of alcohol, but it can definitely benefit a person’s vision.

Those of you who are unaware of AMD, here are some of the main symptoms of the disease:

  • Blurry Vision – Blurry vision, dark spots or white spots might occur in your central vision if you’re suffering from AMD.
  • Color Changes – A changed or diminished perception of color is yet another symptom of AMD.
  • Distorted Vision – People suffering from AMD might also begin to suffer from distorted vision as the straight lines may begin to appear distorted.

Ultimately, the best way of ensuring that you protect yourself from eye diseases is to maintain a healthy lifestyle, regulate your diets, add food items that are beneficial for the eyes and perform regular eye exercises. The red wine study certainly comes as an added incentive of taking care for one’s eyes.

Woman suffering through menopause

Resveralife Studies the Connection Between Menopause, Hormone Therapy and Skin Aging

Vine Vera tries to study the connection between Menopause, Hormone Therapy and Skin Aging with the help of various studies and trials available on the subjects. One of the most common examples of where enthusiasm for a drug’s supposed benefits surpassed supporting research is Menopause Hormone Therapy (HT). This therapy was a major feat in marketing and by the year 2002, almost 38% of older women in the US had taken one form or the other of HT. Although evidence of the relief offered by HT was properly supported by scientific data, there was no concrete proof of the supposed long term benefits that this therapy had to offer. Today, there is adequate data which shows that HT actually poses a number of health risks and as a result, many women have already stopped taking the therapy. However, some still continue to advocate that HT can help menopausal women by combating the signs of aging.

 

The main reason why menopause symptoms are quite evident on the skin is because of the reduction in the production of estrogen, which directly affects the moisture content and the elasticity of the skin. It is believed that lower estrogen levels lead to issues like dryness, sagging, wrinkles and skin aging. However, the converse of this assumption hasn’t been adequately proved either. For example, men with higher levels of estrogen don’t necessarily have better skin.

 

In fact, there is very little evidence which supports the theories that menopause leads to wrinkling. A study known as the Kronos Early Estrogen Prevention Study (KEEPS) had performed a clinical trial with 720 menopausal women. This study found that estrogen wasn’t the main cause which led to skin aging and wrinkling. This study also found that the time lapse in menopausal transitions did not affect the skin either. In fact, amongst all aging factors, only frown lines could be directly related to menopause. All other signs of aging were related to cigarette smoking and the aging process.

 

However, even if estrogen isn’t a major problem, women still prefer to use the therapies to minimize and prevent aging, provided the therapies work. Again, the evidence supporting the effectiveness of these therapies isn’t conclusive either. There were two trials that took place with regards to HT – one with Oral HT and the other with Topical HT. The Oral HT trial was conducted in the year 2008 by the Boston University. This study examined 485 women who were offered two doses of norethindrone acetate and ethinyl estradiol. The results did not show any improvements in terms of skin texture, fine lines or wrinkles. The second trial with Topical HT was also conducted in the year 2009 by the University of Michigan. This study actually found benefits upon topical applications. The study showed that the estradiol cream helped to stimulate collagen production. However, these benefits were only seen on areas of the skin where sun damage wasn’t prevalent. Thus, this study also suggested that topical estrogen also has a very limited use.

 

Another solution that was discussed about was the option of using topical progesterone creams. This cream was used in a clinical trial conducted in the year 2005 by the University of Vienna. The study examined the effects of applying topical progesterone cream daily on the face of a menopausal woman. This study also found that although the cream had significant benefits to offer when it came to reducing fine lines and wrinkles, it could not treat skin dryness. However, this study was preliminary in nature and it was too soon to be used in over the counter products.

 

This goes on to show that even though HT did not offer any significant improvements, progesterone could actually help to combat the signs of aging. This led to the question if there were other solutions available as well. Well, the best way to prevent aging is to actually prevent aging. When it comes to aging, having some level of common sense and self discipline can go a long way. Protecting the skin from sun exposure and quitting smoking can alone help you to ensure that your skin stays young and you don’t succumb to premature aging. Using Retinol based skin care products (a clinically proven anti-ager) can also work wonders when it comes to preventing skin aging.

 

Moreover, the supposed benefits of such treatments have always been talked about. But, what about the negative side effects? Side effects such as melasma, a condition which leads to dark spots on your skin. Melasma is perhaps one of the most well documented and long lasting side effects of HT treatments.

 

This leads us to believe that menopause might have a minor role to play in terms of skin aging, but it is in no ways the main reason behind skin aging among middle aged and older women. What ultimately lead to skin aging are factors like smoking, sun exposure and poor skin care habits. It doesn’t make sense to rely on drugs that have very little clinical data to back them up. What ultimately helps you to keep your skin beautiful and supple is basic common sense and the sense of differentiating the right from the wrong. 

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