Healthy, happy women.

Healthy pH For Your Body Part

“Hey, did I catch you off balance?”  “Were you balancing your books?” “Trying to get your life in balance?” Our government runs on a system of checks and balances and a balance of power. We need to balance work and life, good and bad, reward and punishment.  Our universe depends on balance, the positioning of planets and the forces of motion all depend on balance.  Our bodies depend on balance. If balance weren’t such big deal, why are we all doing yoga?

 In order to maintain equilibrium in our bodies, It is no surprise that balance is also important. Our bodies need to have a  healthy pH balance, that is the alkalinity in our body must be in balance with the acidity in our bodies.

Before we continue it should be noted that the kind of balance we talk about when we talk  about our bodies is not the kind of balance which requires an equal amount on each side, it is the balance of correct proportion.  Just as a beautiful face is not always perfectly symmetrical, a healthy body is not either.  The optimal pH balance for our bodies is a little bit on the alkaline side, with a  pH of 7.4 on a scale ranging from 1-14 and it is suggested that we eat a diet which puts the emphasis on alkaline foods as opposed to acidic food. But  it is not the acid content of the food that makes the difference, it is the way our different body parts respond to the acid.

Blood
When we talk about maintaining a 7.4 pH balance in our body, we really do not need to worry about our blood.  Our lungs and kidneys take care of keeping that number constant.  Rather, it is the body parts whose pH balance is less stable that  we need to worry about.

Cells
The pH levels of our cells tend to vary more than our blood and we need to make sure they stay slightly alkaline, so we need to watch our diet to make sure that they function at their best.  Alkaline diets provide magnesium, which is needed by our enzyme systems and preserve muscle mass while aging.

Urine
 The pH level of our urine is also worrisome,as it tends to vary as well.  To keep it stable, we need to avoid animal protein, grains, soda, beer, and sodium, which are hard for our kidneys to break down.  It is important that we get potassium and minerals from fruit to neutralize the acid.

Stomach
The stomach needs to remain slightly acidic in order to break down food.When you eat, your stomach releases  acid causing your stomach pH to drop to as low as 1 or 2. After the meal is digested, buffers in your stomach, such as mucous and bicarbonate, work to neutralize the acid, bringing your tummy back to a resting rate of 4-5. When levels of acid in our stomach are high, (which happens when we eat protein, especially red meat) our system seeks out alkaline nourishment in our digestive tract.  If it cannot find it, it will draw minerals from our bones. (This is an example of what happens when our bodies are not in balance.) It is why it is so important to eat a diet heavy in nutrients like calcium, magnesium, phosphorous and potassium to make sure our system can find them when it needs to

Skin
The skin needs to be slightly acidic to support the acid mantle.  This is the skin’s barrier It blocks out germs, pollution, and toxins.  When skin is too alkaline, it becomes dry and inflamed. It may stop fighting off enzymes that destroy collagen and cause wrinkles.  The ideal pH level for the skin is 5.5. If it is higher, it signals damage to the acid mantle which exposes your skin to bacteria and UV rays and may be a sign of excessive use of exfoliants and peeling products

If the pH of the skin is lower than 5.5, that probably nears you are overusing products designed to make skin less greasy.  If this is you, pay attention to scrubbing  and hydrating often.

Human neuron

The Cell Transformation that Could Transform Medicine

The treatment and management of diseases and conditions is one of the most heavily studied areas of science. New discoveries are made every day, some of which have the power to transform medical practices. A recent study by molecular and cellular biologists indicates that the way in which personalized medicine is practiced may truly transform. Scientists have been able to use gene insertion to transform one type of cell into another type of cell. Adding genes into the original cells is a highly intricate process that involves a significant time investment. Additionally, when using gene insertion to transform cells, there is the possibility one of the genes meant for insertion could end up on a chromosome and activate a cancer-causing gene. New studies published online by Cell Stem Cell states that scientists have successfully transformed skin cells into neurons without the use of gene insertion.

The Study
The studies published online by Cell Stem Cell assert that scientists have been able to transform one type of cell into another type of cell with a less invasive and time consuming process. The new transforming technique involves the addition of a specific set of chemicals to the cells. Gang Pei, a co-author of one of the studies and a biochemist at the Shanghai Institutes for Biological Sciences in China explains that the crucial element in this new way of transforming cells is the use of small molecule chemicals. These small molecule chemicals go into the cell and enter the nucleus of the cell, the part that contains DNA. From here, the small molecule chemicals are able to alter the activity of a gene. Pei, and the team he led, spent enormous amounts of time researching the exact chemical concoction that can transform cells; in the study they transformed skin cells into neurons. The specific group of chemicals used by Pei and his team are labeled VCRFSGY and these chemicals work in stages. VCRF, the first four chemicals, begin the process by altering physical traits on a gene known as Tuj1 (a gene that is specifically active in neurons). Without the last three chemicals, the altered cell exists in an ambiguous state being neither a skin cell nor a neuron. The SGY chemicals amplify the neurological development that VCRF initiated which results in cells that looked, and acted like, neurons.In a second study, researchers in China were able to achieve the same results in mice using different chemicals.

Why it Matters
With two separate studies, and two sets of chemicals, producing the same results, molecular and cell biologists believe that this process could compete with gene insertion in order to reprogram and transform cells. They believe that the process of using small molecule chemicals will especially benefit the field of personalized medicine. These study is exciting because with these processes, a patient’s own cells can be used to treat illnesses and other conditions. Pei’s team was able to transform skin cells from an Alzheimer’s patient into neurons that exhibited markers of Alzheimer’s disease. With this process, researchers would be able to safely and accurately research the disease and perform drug tests on the transformed cells without endangering the patient.

These studies indicate that medical research and development continues to reach new and exciting heights constantly, which provides the scientific community with hope that disease study will advance to the point where cures are possible. These studies are just the beginning of the powers of cell-transforming technology and only time will tell what will be possible in the future.