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Resveralife Examines Studies on Necessary Quantities of Resveratrol for Effectiveness

The latest research might come as a disappointment to all red wine enthusiasts because it shows that the amount of Resveratrol present in red wine is not enough to bring about skin benefits. Resveratrol, believed to be one of the most effective anti-aging ingredients and antioxidants in the world, is commonly found in the skin of red grapes. People have been consuming the ingredient in their diets for years with the hopes of boosting their anti-aging efforts and get younger looks.

Contrary to what was initially believed, this new study shows that the life-extending and disease-fighting benefits cannot be derived by consuming it through food or red wine. This study was conducted on a population of two villages in Chianti, Italy. A total of 783 men and women who were at least 65 years old were made a part of this study. Their Resveratrol intake was studied for a period of 10 years between 1998 – 2009. The results of this study were recently published in the JAMA Internal Medicine Journal.

Researchers used the subject’s urine and tested them for Resveratol metabolites, instead of asking participants to record their intakes in order to produce effective and accurate results. The study also ensured that less than 1% of its participants took herbal supplements, minerals or vitamins of any kind. Therefore, any increase in the byproducts of Resveratrol could be directly attributed to the food items and drinks consumed.

According to reports, about one-thirds of the participants died during this 9-year study. Furthermore, 4.6% participants developed cancer while 27% of the participants developed cardiovascular diseases. The study revealed no differences in the inflammation, cancer or cardiovascular disease rates, irrespective of whether the participants took Resveratrol or not. Upon first glance, it might come across as a major disappointment for all Resveratrol enthusiasts because the study actually shows that the Resveatrol in the food does not offer any visible benefits to the human body.

However, this was something that was already suspected by experts. The body needs a lot more Resveratrol than what can be consumed through food and red wine in order to produce noticeable changes, reduce inflammation and allow a person to live for longer. According to Dr. David Sinclair, a Harvard University researcher, the amounts of Resveratrol obtained through the diets of humans is actually negligible. Thus, the only way to derive the wonderful benefits that Resveratrol has to offer is to consume it in higher  doses.

This is where an earlier study that we mentioned about proves to be so useful. In fact, this is one of the main reasons why the skin care industry has been showering so much attention on Resveratrol. According to a study that we have already discussed about, topical applications of Resveratrol have proven to be more effective than ingesting it orally. One of the main reasons for this result was that it is possible to include increased amounts of Resveratrol by way of topical applications, thereby allowing the body to enjoy the right amount of Resveratrol that it needs in order to take the most out of the ingredient.

There is no doubt that Resveratrol is still one of the most exciting compounds to have been discovered by mankind. However, we need to be patient and wait for science to understand more about its basic biology and uncover the best possible ways and means of using it. Until then, topical applications of Resveratrol seems to be the best way of deriving benefits from this magical ingredient.

Nude model reflecting on body image

Resveralife on Body Image

Body image simply implies to how one thinks and feels about their body. It involves a number of things such as your emotions, thoughts, actions and perceptions with regards to your body. Body image doesn’t necessarily comprise of what you see when you look into the mirror or what other people think about your body. It essentially deals with how you feel about your body as a whole. Most people end up having the wrong impressions about body image. Having a good body image isn’t necessarily about having a slim-trim figure or looking flawless. Having a good body image is all about feeling happy and satisfied with your body. Things like over-exercising, dieting, low self-esteem, anxiety and depression are more than likely to ruin your body image. To sum up, the term body image simply defines the way a person perceives his/ her body to be and assumes that others perceive the same. Body image is most often affected by social pressure, social media, television, friends and family.

What do the Statistics say?
All you need to do is to read the statistics to understand how people perceive their bodies to be.

  • About 91% of the women are believed to be unhappy with their body image. As a result, they resort to things like dieting in order to get their bodies in shape.
  • Body image is closely related with self esteem. Many adolescents have low self esteem because they “think” that they have a poor body image. This leads to problems like eating disorders, suicidal thoughts, depression, substance use or early sexual activities.
  • Approximately 5.58% of the girls in college feel the need to maintain a particular weight.
  • Almost 40% of the women and 20% of the men have considered getting cosmetic surgeries done. These statistics are the same for all ages, races, and genders.
  • Students who are subjected to mainstream media are more likely to relate body image to looking sexy rather than relating it to their overall appearance.
  • About 95% people having eating disorders are aged between 12 – 25.
  • 38% men sacrifice at least one year of their life in their search for the “perfect body”.
  • Almost 23% of the men and 45% of the women who belong to the healthy weight bracket feel that they are overweight.

How to Improve Your Body Image
Improving your body image has nothing to do with looking sexy, having flawless skin, maintaining a particular figure or whitening your skin tone. There are a number of things that you can do to improve your body image, but first and foremost, you need to transform the way you look at your body. It’s not about looking hot or sexy. Its about feeling happy and satisfied with what you have.

  • Surround yourself with positive, supportive relationships. Although we have nothing against magazines or tabloids, many of them are useless when it comes to helping you improve your body image. A number of tabloids promote negative thoughts by showing you how overweight you are or shaming you for being too skinny. This leads to negative perceptions which ultimately leads to negative relationships. You need to ensure that you fill your surroundings with people who have a positive approach to life and are supportive of you, irrespective of how you “look”.
  • Exercise regularly. Be grateful for what your body is able to do rather than how it appears to be. You don’t have to over-exert yourself or participate in extreme sports to maintain that perfect body image. All you need to do is go for regular jogs and appreciate the fact that your body allows you to move from one place to the other. Hitting the gym is a great idea as well. But, make sure that you hit the gym for the right reasons, and not to “improve” your body image.
  • Eat a healthy, balanced diet. Research has proved that almost all young women and more than half of middle aged women have resorted to things like dieting. Dieting helps you to lose your weight quickly, but the moment you stop, you’re likely to gain it back. This “weight loss, weight gain” seesaw is extremely perilous for the body and it leads to a number of health problems and heart diseases. People who resort to dieting are also known to be susceptible to eating disorders. The best thing to do is to regulate your diet and eat healthy food.
  • Set realistic goals for self-improvement. You need to understand that not a single person is “perfect”. Each human being has his or her flaws. This is what makes us unique. This is what creates and defines our identity. Try to understand that even those perfect looking celebrities have “issues”. Try to set realistic goals for yourself and keep reminding yourself that “real” people are never perfect. Perfect people are only good for one of those wax museums.
  • Avoid negative self-talk. Research has shown that our brains can’t figure out the difference between things that it thinks, says or hears at some level or the other. Therefore, if you tell a person that he/ she needs to lose a couple of pounds, it is the same as telling yourself that you need to lose a couple of pounds. Avoid negative thoughts and don’t dissuade others. Remember, your brain is likely to take in all that information and feel that the messages were directed towards you.
  • Pamper Yourself. Indulge in things like therapeutic massages, proper sleeping hours, relaxing bubble baths or luxurious spa sessions. Pamper your body whenever you get the chance. If you feel good physically, it becomes much easier to enjoy your body and love it for what it is.

Resveratrol's Ability to Treat ANCL

Human prion protein (hPrP), chemical structure. Associated with neurodegenerative diseases, including kuru, BSE and Creutzfeldt-Jakob. Cartoon + wireframe. N- (yellow) to C-term (red) gradient color.Resveratrol, a powerful antioxidant that is found in the skin of red grapes, is extremely famous in the world of skin care because of its unique anti-aging benefits. Recent research now shows that Resveratrol might also be very effective in offering the first cure for a neurodegenerative disease known as ANCL (Adult Onset Neuronal Ceroid Lipofuscinosis).

According to a study that was funded by the BBSRC and AGE UK and was published in the Human Molecular Genetics Journal, a group of University of Liverpool researchers have finally been successful in finding a potential cure for ANCL. Alan Morgan, the lead researcher of this project, states that even though ANCL currently remains to be untreatable, their research allows them to test for compounds that could offer effective treatments. He further states that among all the compounds tested in the first batch, one (Resveratrol) has shown highly encouraging effects.

ANCL is a disease that is known to affect almost 1 out of every 100,000 people in North America and Europe. It mostly affects adults in their mid-thirties and death comes as early as the mid forties. Despite constant research, no cure was found for the disease until now. However, even though previous studies were unsuccessful in finding a cure, they had managed to connect the disease to the DNAJC5 gene.

The latest study used nematode worms to search for cures for the ANCL disease. The disease was introduced into their bodies my mutating the dnj-14 gene, a gene which is quite similar to the DNAJC5 gene in humans. Since these worms have a lifespan of a couple of weeks only, symptoms of the disease were developed within days. This helped in reducing the time frame that was needed to design and study ANCL treatments.

Researchers used this model to test for a number of chemicals. One of the chemicals that was tested on these worms was Resveratrol, and surprisingly, Resveratrol actually managed to cure the disease without even having to act through the SIR-2.1 enzyme. Almost all other potential treatments were forced to act through this enzyme.

These results have encouraged researchers to test for more chemicals and decide whether nematodes can also be used to study for potential treatments against other neurodegenerative diseases that mankind suffers from. These findings go on to suggest that Resveratrol can play a major role in helping humans to prevent diseases and repair the damage caused by diseases. Although scientists have already been studying Resveratrol for many decades, this compound never ceases to amaze.

In fact, in a study conducted in the year 2003, researchers have also managed to prove that using Resveratrol can help in increasing the life span. This was done using short-lived fish as test subjects. Resveratrol helped in increasing their lifespan by as much as 50%. Moreover, the fish that were offered Resveratrol were able to swim and learn new things in their old age better than fish that were not offered Resveratrol.

This leads to the argument that there is still so much more that the world needs to know about Resveratrol. It wouldn’t come as a surprise if we found Resveratrol to become the most important compound known to man in the near future.

Baby with grapes

Resveratrol Update – Resveratrol Examined for Reproductive Benefits

 

A group of experts recently conducted a pilot clinical study in order to determine the effects of Resveratrol on the systematic sex steroid hormones. The study was conducted using 40 subjects who were offered with 1gm of Resveratrol for a total of 12 weeks. 6 of the subjects were withdrawn from the study because of certain adverse effects. However, the other 34 successfully managed to complete the entire Resverarrol intervention. The results obtained by testing these 34 subjects show that although Resveratrol intervention did not bring about significant changes in the estrone, testosterone or estradiol, it did manage to a 10% increase (on an average) in terms of the concentrations of the SHBGs, also known as the sex steroid binding globulins.

However, out of the remaining 36 participants, two subjects suffered from Grade 3 rashes, one participant suffered from a Grade 4 elevation of the liver enzymes. All other issues were Grade 1 or Grade 2 events (considered to be common in such studies). In fact, the most common problems were increased cholesterol levels and diarrhea.

This led the experts to conclude that 1gm of Resveratrol had a favorable effect on the SHBG as well as the estrogen metabolisms for obese postmenopausal women.

As you might already be aware, the risk of breast cancer can be partially determined by a number of factors that relate to your hormones. According to this study, Resveratrol might prove to be extremely useful in moderating these hormonal factors. However, placebo controlled tests are required to confirm these findings and the adverse effects that have been found also need to be observed in a study population before we can offer you with concrete proof.

Pencil eraser erasing leukemia

Resveratrol Update – Resveratrol Aids in Preventing Leukemia?

Pencil eraser erasing leukemia

Cardiotoxicity is considered to be one of the most common side effects of numerous antineoplastic agents like arsenic trioxide, one of the main treatments for a disease known as acute promyelocytic leukemia. Researchers recently investigated the possibility of using a combination of arsenic trioxide and Resveratorl or genistein in creating a cardiac friendly therapeutic strategy for acute promyelocytic leukemia.

 

During the research, potential combinations were explored and the effects of these combinations on reactive oxygen species, autophagy, mitochondrial membrane potential, apoptosis and superoxide dismutase activity were determined. The results of the experiments suggested that about 5 µM of Resveratrol helped in reducing cardiotoxicity caused by arsenic trioxide to a great extent. To get the same amount of benefits, researchers had to use a dosage of genistein that was 10 times stronger than the Resveratrol dosage. Furthermore, administering Resveratrol also boosted the anti-cancer effects of the arsenic trioxide present in the NB4 cells. Resveratrol also aggravated mitochondrial damage and oxidative stress, thereby reflecting its synergy with arsenic trioxide. In addition to these results, using 5 µM of Resveratrol with a singular drug formula of arsenic trioxide lead to an increase in the cellular autophagy activity, thereby indicating the involvement of autophagy-mediated tumor cell death.

 

This study goes a long way in showcasing the importance of Resveratrol in terms of preventing Leukemia. Researchers believe that it is entirely possible to combine Resveratrol to arsenic trioxide in order to prevent cardiotoxicity and achieve better therapeutic effects. However, the poor bioavailability of the compound remains to be a major concern in its clinical applications.

 

Vine Vera Resveratrol Men's collection

Vine Vera Resveratrol Men’s Collection

Anti-aging skin care is not just for women. Our excellent Men’s Collection addresses common male skin issues, after all razor bumps and post-shave irritation on the cheeks is not something women need to worry about! Let your skin soak in all the nourishing vitamins and extracts combined with Resveratrol to leave your skin appearing soft, hydrated, and younger. The collection includes Resveratrol Men’s After Shave Balm, Resveratrol Men’s Sauna Energizing Mask and the Resveratrol Men’s Sauna Serum. Conveniently bundled in 3 simple products, luxury skincare has never been more easy to use.

The Resveratrol Merlot Collection from Vine Vera Cosmetics.

Vine Vera Resveratrol Merlot Collection

Get it all in one collection! Just like Merlot wine, the Vine Vera Merlot Collection is a versatile assortment of skincare products. The Merlot Collection is perfect for anyone looking for a daily regimen in one set. Any healthy skin regimen includes cleansing, toning, a nutritive serum, and a day and night moisturizer. Whether you are just beginning to think about skincare or are continuing to battle the signs of aging, the Resveratrol Merlot Collection will do wonders for your skin. The line includes a Cleansing Kit, Resveratrol Merlot Refining Peeling, Resveratrol Merlot Moisture Day Cream,  and a Resveratrol Merlot Nourishing Night Cream. The Merlot Collection is the perfect starting point to well taken care of skin.

Vine Vera Merlot Collection Demo Part 1


Vine Vera Merlot Collection Demo Part 2

Vine Vera Resveratrol Eye Collection

The area around your eyes is more delicate and vulnerable than other parts of the skin. Protect it with products that are specially formulated to care for these areas. Many people experience unpleasant issues around their eye area like dark circles and crow’s feet. Vine Vera’s Resveratrol Eye Collection was made gentle, yet powerful for daily use. This collection is cutting edge in its use of Resveratrol as a main ingredient for the whole line. New studies about the effectiveness of Resveratrol in the anti-aging arena are multiplying. We have used Resveratrol as the main ingredient of this line to offer you the best possible results in eye skin care.

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