Resveratrol

Resveralife Reviews Resveratrol as a Sleep Aid

Sleeping after taking a sleep aidWhat if we told you that there was a way to make your skin look younger and healthier as well as help your sleep cycles using the same ingredient? Over the years, numerous studies and trials have been conducted around Resveratrol to try and determine the wonders that this miracle ingredient can offer to your skin and your health. Vine Vera recently came across studies which show that apart from offering you with all sorts of skin benefits, Resveratrol can also be used as a sleep aid.

So what is Resveratrol? Well, Resveratrol is an antioxidant that is found in the skin of red grapes, red wine, nuts and other plant sources. It became very popular in the world of skin care because of its anti-aging properties and the fact that topical applications of Resveratrol proved to be far more effective than including Resveratrol in your diet. So where does sleep come in?

Vine Vera reviews a recent study that was conducted by researchers from the Maastricht University Medical Center, Netherlands and was published in the Cell Metabolism Journal. This study states that Resveratrol enabled the bodies reduce the sleeping metabolic rates, increase the muscle efficiency and allow the body to burn the same amount of energy over 24 hours. This study was based on a trial conducted with male subjects who were offered 150mg of Resveratrol every day for a period of 30 days.

Another study published in the Chronobiology International Journal proved to be even more informative. This study tried to research on the effects of Resveratrol on the sleep-wake cycle of a lemur. After 3 weeks of Resveratrol supplementation, the animal displayed an increased proportion of active-awake time. This was also accompanied by a huge reduction in slow-wave sleep and paradoxical sleep. The study also showed that these changes mainly occurred during the resting phase of the lemur sleep-wake cycle. Thus, the data obtained by the study goes on to suggest that Resveratrol might actually be an excellent regulator of sleep-wake rhythms.

A series of clinical trials conducted in Japan have also proved to be highly positive. The subjects of this trial were offered with a single dose of 14mg Resveratrol before they went to sleep. The study found out that Resveratrol considerably helped to improve the well-rested feeling among subjects who had taken these supplements. Sleep observations and brain wave measurements of these subjects further suggested that Resveratrol offered a sufficient improvement in terms of non-REM sleep, which is believed to be the most important aspect of sleeping properly.

These studies make Resveratrol an extremely interesting subject in the study of sleep perturbations that are associated with aging. Although more tests need to be carried out before conclusive evidence can be derived, the chances of a positive relationship between Resveratrol and your sleep cycles certainly seem to be extremely high.

In fact, Japan has already rolled out the first patent to use a Resveratrol based product for sleep improvement based on the human clinical data which indicates the ingredient’s ability to help improve the quality of sleep among humans when compared to placebo.

Doctor measure the waist of a make patient

Vine Vera Researches: Resveratrol a Cure For Metabolic Syndrome? VineVera Reviews

Resveratrol, a natural compound that is found in red wine and in the skin of red grapes, has emerged as one of the most popular skin care ingredients in the world. Vine Vera uses Resveratrol as its signature ingredient, primarily because of the wonders that it has to offer to one’s skin. There are numerous studies that have already shown the wonders that Resveratrol has to offer as a skin care ingredient. However, many more studies that can take Resveratrol research and its uses to an entirely new level are currently in various stages of completion.

Vine Vera reviews a study that was published in the Journal of Clinical Endocrinology & Metabolism. The authors of this study are a group of Danish researchers who tried to determine whether or not Resveratrol could help cure metabolic syndromes, an issue that can cause bone loss. Metabolic syndromes have been linked to low-level inflammation and it is basically a cluster of risk factors that can increase the chances of things like diabetes, heart diseases and strokes. Some of the main risk factors that the body goes through when suffering from the metabolic syndrome include high levels of triglycerides, increased blood pressure, abdominal obesity and reduced density of good cholesterol levels.

According to Marie Juul Ørnstrup, one of the authors of the study who works for the Aarhus University Hospital, Denmark; this study is the first Resveratrol study that tries to determine the potential of Resveratrol as an anti-osteoporosis drug that can help humans.

This study was performed as a double-blinded, placebo controlled trial that tried to assess the signs of bone formation and resorption and bone mineral density in sixty six men who suffered from metabolic syndrome. This trial went on for a period of 16 weeks, where the men were either made to take a placebo, a 500mg dose of Resveratrol or a 75mg dose of Resveratrol two times a day.

According to the results of the trial, men who took the 500mg dose of Resveratrol saw an increase of almost 2.6% in terms of the volumetric bone mineral density of the lumbar spine. Moreover, the group of men who were offered a higher percentage of Resveratrol also managed to see a 16% increase in the BAP levels (Bone formation marker Alkaline Phosphatase levels) when compared to the rest of the group.

Marie states that the findings of this study state that the Resveratrol can actually stimulate the bone-forming cells within the human body. She also mentions that within just four months of being offered with a high dose of Resveratrol, the study observed a significant increase in the BAP levels as well as improvements in the bone mineral density.

Marie believes that this study has actually offered the scientific world with highly encouraging results. Although additional research is still needed before it can be ascertained whether Resveratrol can actually offer these wonders and whether Resveratrol can be used for long-term treatments, but experts from the skin care and scientific world are already excited to find out yet another wonder that Resveratrol has to offer.

Sirtuin structure

Resveralife Examines the Link Between Resveratrol and Longetivity

Vine Vera reviews a recent study that shows how important this Sirutins are for the aging process.

 

This study focused on the SIRT3 gene, a gene that is found in the mitochondria of the cell. It seems that the age gap usually occurs because the system doesn’t function as well as it used to when the body was younger, it suffers from oxidative stress and over the years the stress levels build up as well. Under such conditions, the normal anti-oxidative system cannot take care of the body. This is when it gives into aging.

 

Reports suggest that researchers have finally managed to actually turn back the molecular clock in the blood stem cells of mice by infusing them with a unique longevity gene. Yes, you got that right. The experiment actually managed to rejuvenate aged stem cells, thereby providing new hope for the development of cures for age related diseases in human beings. This study was conducted by the University of California, Berkeley. Researchers associated with the tests believe and this study provides new hope for advancements in the understanding of molecular mechanisms. The findings of the study were also published in the Cell Reports Journal.

 

According to biologists, the SIRT3 gene, a gene that is found in the Sirtuin proteins, played a huge role in allowing aged stem cells to be able to cope up with stress. Researchers infused the blood stem cells of old mice with SIRT3. This led to the formation of new blood cells, thereby representing a reversal in the age decline of the stem cell function of the aged cell.

 

Danica Chen, the head investigator of the study mentions that it is already known that Sirtuins can regulate aging. However, this study can show that Sirtuins can actually reverse age-related degeneration. This is by far one of the most exciting discoveries made by the medical industry since the discovery of Resveratrol.

 

Over the past 10 – 20 years, scientists have managed to make countless breakthroughs when it comes to aging. We might not have the Fountain of Youth as yet, but we’re definitely close. Instead of a being a random and uncontrolled process, aging can actually be controlled. It is believed that as science progresses further, the secrets to the Fountain of Youth shall finally be unlocked in front of mankind.

 

A couple of studies conducted in the recent past had also shown how Resveratrol, the red wine compound, is beneficial for the skin and the body. These studies had shown that Resveratrol is an excellent antioxidant which protects the body from free radical damage and damage from the UVA and UVB rays of the sun. It is also known to be the only polyphenol that can activate the SIRT1 gene. The SIRT1 gene helps in promoting the creation of new cells and also goes a  long way in ensuring that the old ones last for longer.

 

Thus, when you combine the studies of this SIRT1 gene to the results obtained in the University of California study, the results actually look quite promising for all those looking for solutions to aging. It remains to be seen whether the SIRT3 gene can actually help in prolonging life, but Danica pointed out that this wasn’t the main goal of the research. She stated that the main goal was to use the knowledge to treat age-related diseases. Well, if not aging, we’re also happy with the next best thing – cures to age-related diseases.

Many bowls of different super foods

Resveralife on Super Foods Containing Resveratrol

Now found in supplements and many skin care products the phenol compound Resveratrol is being hailed by scientists, health professionals and beauty experts as the newest wonder product due to its many health benefits. However, you do not need to purchase fancy health and beauty products to get your fix of resveratrol as it is found naturally in many food products. Here we take a look at the super foods containing Resveratrol and how they can benefit your health.

Just before we discover what foods contain this wonder product we need to know exactly what it is and what the benefits actually are. Resveratrol is a plant phenol that is a powerful antioxidant as well as anti-inflammatory. Research into the compound has shown some of the many health benefits include lowering cholesterol, targeting insulin resistance which the precursor to diabetes and promoting general good health. As it works on a cellular level to encourage longer cell life it is even thought to slow the onset of Alzheimer’s disease and even limit the spread of cancer cells. Resveratrol’s powerful capabilities of prolonging cell life also make it the must-have ingredient for many anti-aging products.

So, what are the super foods that contain such a miraculous compound? One of the best foods featuring resveratrol is red grapes. They are not only packed with the antioxidant properties of resveratrol but are also full of vitamins and minerals. The grapes loose none of their power when turned into wine; making red wine another popular choice when it comes to intake of resveratrol. Whilst the odd glass can benefit your health you must still only ever drink in moderation; overdoing the alcohol will only cause other health problems.

Staying on the fruit theme, many berries are also a great source of resveratrol. Cranberries, bilberries and especially blueberries are all a good choice. Blueberries are another example of a super food full of useful vitamins and minerals as well as resveratrol.

If fruit really isn’t your thing you may be pleased to know that resveratrol can also be found in foods such as peanuts and dark chocolate both of which are also a good source of manganese; great for strengthening the bones. The benefits are the same whether you eat peanuts as they are or as peanut butter. When it comes to the chocolate, the darker it is the higher the amounts of resveratrol. Again, it is important to remember that whilst these contain good things they are still pretty high in calories so don’t go mad!

For those of you who enjoy a nice cup of tea, why not try Itadori tea?  For many years this has been used as a traditional remedy in China and Japan. It contains resveratrol and is thought to help prevent strokes and heart disease. It is made from Japanese knotweed and tastes very much like rhubarb.

You can get your Resveratrol fix from these foods or for a higher dose try Resveratrol supplements.

man and woman drinking wine

Resveralife Examines Studies on Necessary Quantities of Resveratrol for Effectiveness

The latest research might come as a disappointment to all red wine enthusiasts because it shows that the amount of Resveratrol present in red wine is not enough to bring about skin benefits. Resveratrol, believed to be one of the most effective anti-aging ingredients and antioxidants in the world, is commonly found in the skin of red grapes. People have been consuming the ingredient in their diets for years with the hopes of boosting their anti-aging efforts and get younger looks.

Contrary to what was initially believed, this new study shows that the life-extending and disease-fighting benefits cannot be derived by consuming it through food or red wine. This study was conducted on a population of two villages in Chianti, Italy. A total of 783 men and women who were at least 65 years old were made a part of this study. Their Resveratrol intake was studied for a period of 10 years between 1998 – 2009. The results of this study were recently published in the JAMA Internal Medicine Journal.

Researchers used the subject’s urine and tested them for Resveratol metabolites, instead of asking participants to record their intakes in order to produce effective and accurate results. The study also ensured that less than 1% of its participants took herbal supplements, minerals or vitamins of any kind. Therefore, any increase in the byproducts of Resveratrol could be directly attributed to the food items and drinks consumed.

According to reports, about one-thirds of the participants died during this 9-year study. Furthermore, 4.6% participants developed cancer while 27% of the participants developed cardiovascular diseases. The study revealed no differences in the inflammation, cancer or cardiovascular disease rates, irrespective of whether the participants took Resveratrol or not. Upon first glance, it might come across as a major disappointment for all Resveratrol enthusiasts because the study actually shows that the Resveatrol in the food does not offer any visible benefits to the human body.

However, this was something that was already suspected by experts. The body needs a lot more Resveratrol than what can be consumed through food and red wine in order to produce noticeable changes, reduce inflammation and allow a person to live for longer. According to Dr. David Sinclair, a Harvard University researcher, the amounts of Resveratrol obtained through the diets of humans is actually negligible. Thus, the only way to derive the wonderful benefits that Resveratrol has to offer is to consume it in higher  doses.

This is where an earlier study that we mentioned about proves to be so useful. In fact, this is one of the main reasons why the skin care industry has been showering so much attention on Resveratrol. According to a study that we have already discussed about, topical applications of Resveratrol have proven to be more effective than ingesting it orally. One of the main reasons for this result was that it is possible to include increased amounts of Resveratrol by way of topical applications, thereby allowing the body to enjoy the right amount of Resveratrol that it needs in order to take the most out of the ingredient.

There is no doubt that Resveratrol is still one of the most exciting compounds to have been discovered by mankind. However, we need to be patient and wait for science to understand more about its basic biology and uncover the best possible ways and means of using it. Until then, topical applications of Resveratrol seems to be the best way of deriving benefits from this magical ingredient.

Resveratrol's Ability to Treat ANCL

Human prion protein (hPrP), chemical structure. Associated with neurodegenerative diseases, including kuru, BSE and Creutzfeldt-Jakob. Cartoon + wireframe. N- (yellow) to C-term (red) gradient color.Resveratrol, a powerful antioxidant that is found in the skin of red grapes, is extremely famous in the world of skin care because of its unique anti-aging benefits. Recent research now shows that Resveratrol might also be very effective in offering the first cure for a neurodegenerative disease known as ANCL (Adult Onset Neuronal Ceroid Lipofuscinosis).

According to a study that was funded by the BBSRC and AGE UK and was published in the Human Molecular Genetics Journal, a group of University of Liverpool researchers have finally been successful in finding a potential cure for ANCL. Alan Morgan, the lead researcher of this project, states that even though ANCL currently remains to be untreatable, their research allows them to test for compounds that could offer effective treatments. He further states that among all the compounds tested in the first batch, one (Resveratrol) has shown highly encouraging effects.

ANCL is a disease that is known to affect almost 1 out of every 100,000 people in North America and Europe. It mostly affects adults in their mid-thirties and death comes as early as the mid forties. Despite constant research, no cure was found for the disease until now. However, even though previous studies were unsuccessful in finding a cure, they had managed to connect the disease to the DNAJC5 gene.

The latest study used nematode worms to search for cures for the ANCL disease. The disease was introduced into their bodies my mutating the dnj-14 gene, a gene which is quite similar to the DNAJC5 gene in humans. Since these worms have a lifespan of a couple of weeks only, symptoms of the disease were developed within days. This helped in reducing the time frame that was needed to design and study ANCL treatments.

Researchers used this model to test for a number of chemicals. One of the chemicals that was tested on these worms was Resveratrol, and surprisingly, Resveratrol actually managed to cure the disease without even having to act through the SIR-2.1 enzyme. Almost all other potential treatments were forced to act through this enzyme.

These results have encouraged researchers to test for more chemicals and decide whether nematodes can also be used to study for potential treatments against other neurodegenerative diseases that mankind suffers from. These findings go on to suggest that Resveratrol can play a major role in helping humans to prevent diseases and repair the damage caused by diseases. Although scientists have already been studying Resveratrol for many decades, this compound never ceases to amaze.

In fact, in a study conducted in the year 2003, researchers have also managed to prove that using Resveratrol can help in increasing the life span. This was done using short-lived fish as test subjects. Resveratrol helped in increasing their lifespan by as much as 50%. Moreover, the fish that were offered Resveratrol were able to swim and learn new things in their old age better than fish that were not offered Resveratrol.

This leads to the argument that there is still so much more that the world needs to know about Resveratrol. It wouldn’t come as a surprise if we found Resveratrol to become the most important compound known to man in the near future.

Baby with grapes

Resveratrol Update – Resveratrol Examined for Reproductive Benefits

 

A group of experts recently conducted a pilot clinical study in order to determine the effects of Resveratrol on the systematic sex steroid hormones. The study was conducted using 40 subjects who were offered with 1gm of Resveratrol for a total of 12 weeks. 6 of the subjects were withdrawn from the study because of certain adverse effects. However, the other 34 successfully managed to complete the entire Resverarrol intervention. The results obtained by testing these 34 subjects show that although Resveratrol intervention did not bring about significant changes in the estrone, testosterone or estradiol, it did manage to a 10% increase (on an average) in terms of the concentrations of the SHBGs, also known as the sex steroid binding globulins.

However, out of the remaining 36 participants, two subjects suffered from Grade 3 rashes, one participant suffered from a Grade 4 elevation of the liver enzymes. All other issues were Grade 1 or Grade 2 events (considered to be common in such studies). In fact, the most common problems were increased cholesterol levels and diarrhea.

This led the experts to conclude that 1gm of Resveratrol had a favorable effect on the SHBG as well as the estrogen metabolisms for obese postmenopausal women.

As you might already be aware, the risk of breast cancer can be partially determined by a number of factors that relate to your hormones. According to this study, Resveratrol might prove to be extremely useful in moderating these hormonal factors. However, placebo controlled tests are required to confirm these findings and the adverse effects that have been found also need to be observed in a study population before we can offer you with concrete proof.